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Transform Your Supply Chain with Seamless EDI Integration

Enable EDI data exchange with all network partners through a single link.

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Enable and manage end-to-end network EDI data exchange with your supply chain.

Ensure secure, reliable, and compliant electronic data interchange across your end-to-end supply chain of suppliers, customers, and contract partners.

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REALIZE DIGITAL TRANSACTION EXCHANGE

Leverage B2N Integrate-OnceTM integration model to link all network partners

Digitalize transactions and processes for buy/sell commerce, external manufacturing, logistics, and more

Feed your enterprise systems with clean real-time data from all supply chain partners

Ensure controlled, compliant data exchange at every step

Why EDI Matters for Life Sciences

In today’s complex and highly regulated life sciences supply chains, speed, accuracy, and compliance are critical. Electronic Data Interchange (EDI) is the standard technology that enables organizations to exchange important business documents such as purchase orders, invoices, and shipping notices quickly, securely, and without manual intervention. By using standardized message formats such as ANSI X12 and EDIFACT, EDI ensures secure, structured, and traceable data flow across internal systems and external partners—from manufacturers and CMOs to wholesalers, distributors, and healthcare providers.

2025-Supply-Chain-Predictions

 

EDI Standards: ANSI X12 and EDIFACT

TraceLink Supports Both ANSI X12 and EDIFACT
 

With TraceLink’s Integrate-Once model, you don’t need to choose one over the other. Our platform enables simultaneous support for both formats—allowing you to globally connect on a single platform with suppliers, customers, and contract partners using the most appropriate and compliant standard.

ANSI X12

Used primarily in North America, ANSI X12 is a structured EDI format with numeric transaction codes like 850 (Purchase Order) and 810 (Invoice). It’s widely adopted in U.S.-based pharma, healthcare, and retail industries.

  • Region: North America
  • Structure: Segment-based (e.g., ISA, GS, ST)
  • Industries: Healthcare, Life Sciences, Retail
  • Flexibility: Highly customizable
  • Adoption Speed: Fast setup for U.S.-based partners
  • Format Style: Numeric transaction sets (e.g., 850 = Purchase)

EDIFACT

Developed by the United Nations, EDIFACT is a global standard for EDI communication. It uses alphanumeric message types like ORDERS and INVOIC and is commonly used across Europe, Asia, and global supply chains.

  • Region: Global (Europe, Asia, LATAM)
  • Structure: Message-based (e.g., UNH, UNT)
  • Industries: Manufacturing, Trade, Transport
  • Flexibility: Standardized format
  • Compliance: Ideal for international trade regulations
  • Format Style: Alphanumeric message types (e.g., ORDERS = Purchase Order, INVOIC = Invoice)

Industry needs

How TraceLink Enables EDI Integration at Scale

TraceLink’s B2N Integrate-Once model and OPUS platform streamline complex supply chain integrations by enabling any company to link once to TraceLink and instantly access a network of trading partners—eliminating the need for multiple point-to-point connections.

Powered by OPUS, TraceLink enables:

Data Mapping and Partner Onboarding

Flexible data mapping and transformation across formats / protocols using network profiles speed onboarding and connectivity.

Data Mapping and Partner Onboarding
Real-Time Visibility and Control

Monitor, track, and troubleshoot transactions across your supply chain with full transparency enabling proactive exception management.

Real-Time Visibility and Control
Automate Complex Workflows

Orchestrate transactions order-to-cash, demand forecasting, inventory management and other processes with full validation and routing.

Automate Complex Workflows
Unify Partner Connectivity

Leverage a single EDI platform for critical data exchange with your entire global supply chain network.

Unify Partner Connectivity

 

 

TraceLink EDI Transaction Types

TraceLink supports a wide range of EDI transaction codes across commercial buy/sell, external manufacturing, logistics, transportation, and other critical supply chain processes. Here’s a quick look at some of the key EDI messages we handle:

 

Filters

  • -- All Business Segments --
  • Manufacturer
  • CMO / CPO
  • Wholesale Distributor
  • Logistics
  • Pharmacy
  • Healthcare / Hospital

  • -- All Orchestration Types --
  • Commerce
  • Logistics
  • External Manufacturing
  • Transportation
  • Serialization-Track and Trace

  • -- All Business Processes --
  • Order-to-Cash
  • Procure-to-Pay
  • Inventory Management
  • Demand & Forecast Management
  • Order Management & Fulfillment
  • Production Tracking
  • Quality, Risk, and Recall Management
  • Financial Reconciliation & Chargebacks
  • Returns & Reverse Logistics
  • Serialization - Track-and-Trace - Compliance
  • Supplier and Partner Onboarding & Qualification
  • Capacity and Supply Assurance Management
  • Master Data Management & Data Quality
  • Exception Management & Issue Resolution
  • Sustainability & ESG Data Collection

  • -- All Transaction Formats --
  • EDI ANSI X12
  • EDIFACT
TransactionTransaction FormatTransaction CodeBusiness Processes Business SegmentOrchestration Type
Advance Ship NoticeEDI ANSI X12856Order-to-Cash, Procure-to-Pay, Order Management & Fulfillment, Financial Reconciliation & Chargebacks, Returns & Reverse Logistics, Capacity and Supply Assurance Management, Sustainability & ESG Data CollectionLearn MoreManufacturer, CMO / CPO, Wholesale Distributor, Logistics, Pharmacy, Healthcare / HospitalCommerce, Logistics, External Manufacturing, Transportation
Advance Ship NoticeEDIFACTDESADVOrder-to-Cash, Procure-to-Pay, Order Management & Fulfillment, Financial Reconciliation & Chargebacks, Returns & Reverse Logistics, Capacity and Supply Assurance Management, Sustainability & ESG Data CollectionLearn MoreManufacturer, CMO / CPO, Wholesale Distributor, Logistics, Pharmacy, Healthcare / HospitalCommerce, Logistics, External Manufacturing, Transportation
Batch ClosureEDI ANSI X12947Production Tracking, Quality, Risk, and Recall ManagementLearn MoreManufacturer, CMO / CPOExternal Manufacturing
Carrier Shipment StatusEDI ANSI X12214Order-to-Cash, Procure-to-Pay, Order Management & Fulfillment, Returns & Reverse LogisticsLearn MoreLogisticsLogistics, Transportation
Credit/Debit AdjustmentEDI ANSI X12812Order-to-Cash, Procure-to-Pay, Order Management & Fulfillment, Financial Reconciliation & Chargebacks, Returns & Reverse LogisticsLearn MoreManufacturer, CMO / CPO, Wholesale Distributor, Pharmacy, Healthcare / HospitalCommerce, External Manufacturing
Supplier Credit Debit AdjustmentEDI ANSI X12812Order-to-Cash, Procure-to-Pay, Order Management & Fulfillment, Financial Reconciliation & Chargebacks, Returns & Reverse LogisticsLearn MoreManufacturer, CMO / CPO, Wholesale Distributor, Logistics, Pharmacy, Healthcare / HospitalCommerce, External Manufacturing
Provider Credit Debit AdjustmentEDI ANSI X12812Order-to-Cash, Procure-to-Pay, Order Management & Fulfillment, Financial Reconciliation & Chargebacks, Returns & Reverse LogisticsLearn MoreHealthcare / HospitalCommerce, External Manufacturing
Customer Credit Debit AdjustmentEDI ANSI X12812Order-to-Cash, Procure-to-Pay, Order Management & Fulfillment, Financial Reconciliation & Chargebacks, Returns & Reverse LogisticsLearn MoreManufacturer, CMO / CPO, Wholesale Distributor, Logistics, Pharmacy, Healthcare / HospitalCommerce, External Manufacturing
Forecast Planning ScheduleEDI ANSI X12830Order-to-Cash, Procure-to-Pay, Demand & Forecast Management, Capacity and Supply Assurance ManagementLearn MoreManufacturer, CMO / CPO, Wholesale Distributor, Logistics, Pharmacy, Healthcare / HospitalCommerce, Logistics, External Manufacturing
Forecast Planning ScheduleEDIFACTDELFOROrder-to-Cash, Procure-to-Pay, Demand & Forecast Management, Capacity and Supply Assurance ManagementLearn MoreManufacturer, CMO / CPO, Wholesale Distributor, Logistics, Pharmacy, Healthcare / HospitalCommerce, Logistics, External Manufacturing
Forecast Planning Schedule ResponseEDI ANSI X12830Order-to-Cash, Procure-to-Pay, Demand & Forecast Management, Capacity and Supply Assurance ManagementLearn MoreManufacturer, CMO / CPO, Wholesale Distributor, Logistics, Pharmacy, Healthcare / HospitalCommerce, Logistics, External Manufacturing
Inventory AdjustmentEDI ANSI X12947Inventory Management, Order Management & Fulfillment, Capacity and Supply Assurance Management, Exception Management & Issue ResolutionLearn MoreManufacturer, CMO / CPO, Wholesale Distributor, Logistics, Pharmacy, Healthcare / HospitalCommerce, Logistics, External Manufacturing, Transportation
Inventory Balance ReportEDI ANSI X12846Inventory Management, Order Management & Fulfillment, Capacity and Supply Assurance ManagementLearn MoreManufacturer, CMO / CPO, Wholesale Distributor, Logistics, Pharmacy, Healthcare / HospitalCommerce, Logistics, External Manufacturing, Transportation
Inventory Balance ReportEDIFACTINVRPTInventory Management, Order Management & Fulfillment, Capacity and Supply Assurance ManagementLearn MoreManufacturer, CMO / CPO, Wholesale Distributor, Logistics, Pharmacy, Healthcare / HospitalCommerce, Logistics, External Manufacturing, Transportation
InvoiceEDI ANSI X12810Order-to-Cash, Procure-to-Pay, Financial Reconciliation & Chargebacks, Returns & Reverse Logistics, Sustainability & ESG Data CollectionLearn MoreManufacturer, CMO / CPO, Wholesale Distributor, Logistics, Pharmacy, Healthcare / HospitalCommerce, Logistics, External Manufacturing
InvoiceEDIFACTINVOICOrder-to-Cash, Procure-to-Pay, Financial Reconciliation & Chargebacks, Returns & Reverse Logistics, Sustainability & ESG Data CollectionLearn MoreManufacturer, CMO / CPO, Wholesale Distributor, Logistics, Pharmacy, Healthcare / HospitalCommerce, Logistics, External Manufacturing
Materials ConsumedEDI ANSI X12947Production Tracking, Inventory ManagementLearn MoreManufacturer, CMO / CPOExternal Manufacturing
Materials IssuedEDI ANSI X12947Production Tracking, Inventory ManagementLearn MoreManufacturer, CMO / CPOExternal Manufacturing
Materials ProducedEDI ANSI X12947Production Tracking, Inventory ManagementLearn MoreManufacturer, CMO / CPOExternal Manufacturing
Order Status ReportEDI ANSI X12870Order-to-Cash, Procure-to-Pay, Order Management & Fulfillment, Returns & Reverse LogisticsLearn MoreManufacturer, CMO / CPO, Wholesale Distributor, Logistics, PharmacyCommerce, Logistics, External Manufacturing
Purchase Order AcknowledgementEDI ANSI X12855Order-to-Cash, Procure-to-Pay, Order Management & Fulfillment, Sustainability & ESG Data CollectionLearn MoreManufacturer, CMO / CPO, Wholesale Distributor, Logistics, Pharmacy, Healthcare / HospitalCommerce, Logistics, External Manufacturing
Purchase Order AcknowledgementEDIFACTORDRSPOrder-to-Cash, Procure-to-Pay, Order Management & Fulfillment, Sustainability & ESG Data CollectionLearn MoreManufacturer, CMO / CPO, Wholesale Distributor, Logistics, Pharmacy, Healthcare / HospitalCommerce, Logistics, External Manufacturing
Price Authorization Acknowledgement/StatusEDI ANSI X12845Order-to-Cash, Procure-to-Pay, Financial Reconciliation & ChargebacksLearn MoreManufacturer, Wholesale Distributor, Logistics, Pharmacy, Healthcare / HospitalCommerce, Logistics
Price/Sales CatalogEDI ANSI X12832Order-to-Cash, Procure-to-Pay, Financial Reconciliation & ChargebacksLearn MoreManufacturer, Wholesale Distributor, Logistics, Pharmacy, Healthcare / HospitalCommerce, Logistics
Product ActivityEDI ANSI X12852Order-to-Cash, Procure-to-Pay, Inventory Management, Demand & Forecast Management, Order Management & Fulfillment, Financial Reconciliation & ChargebacksLearn MoreManufacturer, Wholesale Distributor, Logistics, Pharmacy, Healthcare / HospitalCommerce, Logistics
Product Transfer & ResaleEDI ANSI X12867Order-to-Cash, Procure-to-Pay, Inventory Management, Demand & Forecast Management, Order Management & Fulfillment, Financial Reconciliation & ChargebacksLearn MoreManufacturer, Wholesale Distributor, Logistics, Pharmacy, Healthcare / HospitalCommerce, Logistics
Product Transfer Account Adjustment (Chargeback Request)EDI ANSI X12844Financial Reconciliation & ChargebacksLearn MoreManufacturer, Wholesale DistributorCommerce
Product Transfer Account Adjustment (Chargeback Response)EDI ANSI X12849Financial Reconciliation & ChargebacksLearn MoreManufacturer, Wholesale DistributorCommerce
Purchase OrderEDI ANSI X12850Order-to-Cash, Procure-to-Pay, Order Management & Fulfillment, Financial Reconciliation & Chargebacks, Sustainability & ESG Data CollectionLearn MoreManufacturer, CMO / CPO, Wholesale Distributor, Logistics, Pharmacy, Healthcare / HospitalCommerce, Logistics, External Manufacturing
Purchase OrderEDIFACTORDERSOrder-to-Cash, Procure-to-Pay, Order Management & Fulfillment, Financial Reconciliation & Chargebacks, Sustainability & ESG Data CollectionLearn MoreManufacturer, CMO / CPO, Wholesale Distributor, Logistics, Pharmacy, Healthcare / HospitalCommerce, Logistics, External Manufacturing
Receiving Advice AcceptanceEDI ANSI X12861Order-to-Cash, Procure-to-Pay, Order Management & FulfillmentLearn MoreManufacturer, CMO / CPO, Wholesale Distributor, Logistics, Pharmacy, Healthcare / HospitalCommerce, Logistics, External Manufacturing
RemittanceEDI ANSI X12820Order-to-Cash, Procure-to-Pay, Financial Reconciliation & Chargebacks, Sustainability & ESG Data CollectionLearn MoreManufacturer, CMO / CPO, Wholesale Distributor, Logistics, Pharmacy, Healthcare / HospitalCommerce, Logistics, External Manufacturing
Return Authorization RequestEDI ANSI X12180Returns & Reverse LogisticsLearn MoreManufacturer, CMO / CPO, Wholesale Distributor, Logistics, Pharmacy, Healthcare / HospitalCommerce, Logistics
Return Authorization ResponseEDI ANSI X12180Returns & Reverse LogisticsLearn MoreManufacturer, CMO / CPO, Wholesale Distributor, Logistics, Pharmacy, Healthcare / HospitalCommerce, Logistics
Routing and Carrier InstructionsEDI ANSI X12853Order-to-Cash, Procure-to-Pay, Order Management & Fulfillment, Returns & Reverse LogisticsLearn MoreManufacturer, CMO / CPO, Wholesale Distributor, Logistics, Pharmacy, Healthcare / HospitalLogistics, Transportation
Warehouse Ship OrderEDI ANSI X12940Order-to-Cash, Procure-to-Pay, Order Management & Fulfillment, Returns & Reverse LogisticsLearn MoreManufacturer, CMO / CPO, Wholesale Distributor, Logistics, Pharmacy, Healthcare / HospitalCommerce, Logistics, Transportation
Warehouse Shipping AdviceEDI ANSI X12945Order-to-Cash, Procure-to-Pay, Order Management & Fulfillment, Returns & Reverse LogisticsLearn MoreManufacturer, CMO / CPO, Wholesale Distributor, Logistics, Pharmacy, Healthcare / HospitalCommerce, Logistics, Transportation
Warehouse Stock Transfer Shipment AdviceEDI ANSI X12943Order-to-Cash, Procure-to-Pay, Order Management & Fulfillment, Returns & Reverse LogisticsLearn MoreManufacturer, CMO / CPO, Wholesale Distributor, Logistics, Pharmacy, Healthcare / HospitalCommerce, Logistics, Transportation
Warehouse Stock Transfer Receipt AdviceEDI ANSI X12944Order-to-Cash, Procure-to-Pay, Order Management & Fulfillment, Returns & Reverse LogisticsLearn MoreManufacturer, CMO / CPO, Wholesale Distributor, Logistics, Pharmacy, Healthcare / HospitalCommerce, Logistics, Transportation

 

For Internal 34

How Does TraceLink Support Real-Time Transaction Exchange

Learn how TraceLink MINT enables you and your suppliers to exchange POs, PO acknowledgements, invoices, ASNs, and much more in real time—and see how much it costs!

Learn More
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Digital Invoicing Boosts Cash Flow & strengthens customer trust

Discover how TraceLink MINT for Commerce can revolutionize your invoicing process and fostering stronger customer trust.

Learn More

Why Trust TraceLink for EDI?

Built for Complex, Regulated Supply Chains

Compliant and Secure

Seamless Integration Across Your Supply Chain

Scalable and Reliable

Network Advantages

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Built for Complex, Regulated Supply Chains

EDI solutions designed specifically for security and control in life sciences, healthcare, and other complex global supply chains.

use cases

Compliant and Secure

TraceLink's network integration and data architecture is designed to ensure trust, security, data interoperability and integrity, and legal compliance in the exchange of critical business data between companies.

Data exchange

Seamless Integration Across Your Supply Chain

Link easily with a single integration to all your suppliers, customers, and contract partners by exchanging transactions in the format they prefer.

Digital Network

Scalable and Reliable

Built on TraceLink’s proven platform and the world's largest life sciences and healthcare network handling billions of transactions annually across hundreds of thousands of entities.

Analytics

Network Advantages

Access the largest digital supply network for life sciences, healthcare, OTC and other regulated markets, speeding partner onboarding and improving collaboration with pre-integrated network partners.

What Our Customers Have to Say

Leading life sciences and healthcare companies trust TraceLink to digitally link their supply chain, improve productivity and agility across their supply chain operations, and drive business growth. Here's what they’re saying:

TraceLink customers can exchange business information with all partners through a single integration in their preferred format without maintaining separate integrations for each customer and partner. TraceLink supports all transaction types and maps via an ever-expanding catalog as customers needs evolve and mature.

Simon Ellis

Group Vice President and Leader of Global Supply Chain Strategies Practices

IDC

Networking with our trade partners is obviously very important. You can't do each one individually. It is nice to have one system that they can all go through.

Tyler Martinson

Pharmacy Manager

Sentara Health

As a fast-growing CPO, we're committed to operating with the agility and transparency that the next generation of pharma and biotech companies demands. MINT gives us the platform we need to automate the exchange of business transactions with any partner system.

Alberto Bartolini

CEO

CIT Srl

Targated Recalls

Ready to Streamline Your Supply Chain with TraceLink EDI?

Connect with a TraceLink expert today to explore how we can transform your digital operations.

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