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Enable Seamless, Scalable B2B Integration Across Your Supply Chain

TraceLink delivers flexible, multi-modal B2B connectivity supporting real-time APIs, sFTP, and email to automate data exchange across your partner network. Powered by the OPUS platform and our B2N Integrate-Once™ model, you link once and integrate with any partner no custom interfaces required.

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Accelerate Real-Time Collaboration with a Unified Integration Framework

Seamlessly link your ERP, WMS, MES, or custom systems using TraceLink’s B2B connectivity

Automate key workflows like order processing, shipment tracking, invoicing, and product verification

Exchange structured data in real time with built-in validation, orchestration, and compliance checks

Support asynchronous file transfers via sFTP or email for legacy or low-tech partners

Industry needs

Multi-Modal B2B Integration Built for Any Partner, Any Process

TraceLink’s B2B integration framework enables secure, real-time data exchange with all your supply chain partners—regardless of size, system, or technical maturity. Built on a differentiated, event-driven architecture and powered by the OPUS platform, TraceLink’s B2N Integrate-Once™ model allows you to link once and integrate everywhere without custom interfaces or complex middleware. 

Unify Partner Connectivity

Link with 100% of your supply chain partners regardless of their integration method through a single, secure connection.

Unify Partner Connectivity
Support Any Integration Method

Exchange data via real-time APIs, asynchronous sFTP, or structured email ensuring every partner can participate.

Support Any Integration Method
Automate Complex Workflows

Orchestrate transactions such as order processing, serialized shipping, invoicing, and regulatory reporting with full validation and routing.

Automate Complex Workflows
Real-Time Visibility and Control

Monitor, track, and troubleshoot transactions across your supply chain with full transparency enabling proactive exception management.

Real-Time Visibility and Control
Supported B2B Integration Methods

Link Actions

Link Actions are TraceLink’s pre-defined, network-based transaction types that enable real-time, API-driven integration across the life sciences supply chain. Each Link Action represents a specific business transaction or data event such as sending a purchase order, receiving a serialized shipment, or submitting an invoice that can be securely and reliably exchanged between systems and partners.

Built on TraceLink’s event-driven architecture, Link Actions ensure that every transaction is validated, orchestrated, and securely delivered—regardless of your partner’s system or technical capability. Once configured, a Link Action can be reused across all your partners, accelerating onboarding and reducing integration complexity.

Key Capabilities
  • Real-time API integration with event-driven processing
  • Pre-built transaction types for rapid partner onboarding
  • Guaranteed delivery, validation, and audit trail
  • Seamless interoperability across all TraceLink-linked partners
Benefits
  • Standardized, reusable integration across all partners
  • Reduces time-to-value with out-of-the-box orchestration
  • Fully aligned with compliance and serialization mandates

TraceLink supports a wide range of standardized Link Actions essential for life sciences supply chain operations—enabling real-time, automated data exchange across your partner ecosystem. Here’s a quick look at some of the key transaction types we support:

 
Systems EnabledTransaction Business SegmentOrchestration
NetSuite IBAdvance Ship NoticeLearn MoreDirect Material SupplierLogistics
MSD BC IBAdvance Ship NoticeLearn MoreDirect Material SupplierLogistics
NetSuite IBInvoiceLearn MoreHealthcare Provider & Retail PharmacyDirect Material Supply
MSD BC IBInvoiceLearn MoreHealthcare Provider & Retail PharmacyDirect Material Supply
NetSuite PO IB/OBPurchase OrderLearn MoreThird Party LogisticsClinical Supply
MSD BC IB/OBPurchase OrderLearn MoreThird Party LogisticsClinical Supply
Sales Order OBPurchase OrderLearn MoreThird Party LogisticsClinical Supply

 

Other XML APIs

TraceLink provides flexible, partner-specific XML APIs that allow life sciences companies to meet unique business and technical requirements. These APIs are designed for situations where data formats, business logic, or workflows vary by partner or system—such as legacy ERP integrations, regional regulatory submissions, or specialized supply chain processes.

Unlike rigid, one-size-fits-all interfaces, TraceLink’s XML APIs can be customized to support a wide range of transaction types and data structures. Whether you need to send non-standard ASNs, ingest custom serialization events, or transform product master data into a partner-specific format, these APIs give you the control and adaptability to integrate on your termswhile still benefiting from centralized orchestration, validation, and monitoring.

By leveraging the OPUS platform and B2N Integrate-Once™ model, these custom XML APIs ensure that even the most unique workflows are seamlessly integrated into your broader digital supply network.

Key Capabilities
  • Schema-validated XML payloads
  • Custom transformations and routing logic
  • Bi-directional data exchange (push/pull)
  • Integration with ERP, WMS, MES, and custom systems
  • Full audit trail and monitoring for compliance and troubleshooting
Benefits
  • Tailored to meet specific partner or system requirements
  • Enables integration with legacy or proprietary systems
  • Maintains centralized orchestration and auditability

XML APIs support flexible, partner-specific integrations for unique business needs. Here’s a quick look at some of the custom transaction types TraceLink enables:

 

TransactionTransaction FormatTransaction Code Business SegmentOrchestration
Advance Ship NoticeB2B Other XML APIXML IBLearn MoreDirect Material SupplierLogistics
Purchase OrderB2B Other XML APIcXML IBLearn MoreThird Party LogisticsClinical Supply
SOM Product ReleaseB2B Other XML APITL XMLLearn MoreLife Sciences CompanyExternal Manufacturing
SOM Sales ShipmentB2B Other XML APITL XMLLearn MoreLife Sciences CompanyExternal Manufacturing
SOM ReceiptB2B Other XML APITL XMLLearn MoreLife Sciences CompanyExternal Manufacturing
SOM ESM Sales ShipmentB2B Other XML APITL XMLLearn MoreLife Sciences CompanyExternal Manufacturing
SOM ESM ReceiptB2B Other XML APITL XMLLearn MoreLife Sciences CompanyExternal Manufacturing
SOM Take Product SampleB2B Other XML APITL XMLLearn MoreLife Sciences CompanyExternal Manufacturing
SOM Country ClearanceB2B Other XML APITL XMLLearn MoreLife Sciences CompanyExternal Manufacturing
SOM Aggregation UpdateB2B Other XML APITL XMLLearn MoreLife Sciences CompanyExternal Manufacturing
SOM Market ReleaseB2B Other XML APITL XMLLearn MoreLife Sciences CompanyExternal Manufacturing
SOM Void ShipmentB2B Other XML APITL XMLLearn MoreLife Sciences CompanyExternal Manufacturing
Serialized ShipmentsB2B Other XML APIEPCIS 1.2Learn MoreLife Sciences CompanyExternal Manufacturing
SOM Sales ShipmentB2B Other XML APIEPCIS 1.2Learn MoreLife Sciences CompanyExternal Manufacturing
SOM ESM Update Lot InformationB2B Other XML APIEPCIS 1.2Learn MoreLife Sciences CompanyExternal Manufacturing
SOM DecommissionB2B Other XML APIEPCIS 1.2Learn MoreLife Sciences CompanyExternal Manufacturing
SOM ESM DecommissionB2B Other XML APIEPCIS 1.2Learn MoreLife Sciences CompanyExternal Manufacturing
SOM DestroyB2B Other XML APIEPCIS 1.2Learn MoreLife Sciences CompanyExternal Manufacturing
SOM ESM DestroyB2B Other XML APIEPCIS 1.2Learn MoreLife Sciences CompanyExternal Manufacturing
SOM Product ReleaseB2B Other XML APIEPCIS 1.2Learn MoreLife Sciences CompanyExternal Manufacturing
SOM Shipment EventB2B Other XML APIEPCIS 1.2Learn MoreLife Sciences CompanyExternal Manufacturing
SOM ReceiptB2B Other XML APIEPCIS 1.2Learn MoreLife Sciences CompanyExternal Manufacturing
SOM ESM Sales ShipmentB2B Other XML APIEPCIS 1.2Learn MoreLife Sciences CompanyExternal Manufacturing
SOM ESM ReceiptB2B Other XML APIEPCIS 1.2Learn MoreLife Sciences CompanyExternal Manufacturing
SOM Take Product SampleB2B Other XML APIEPCIS 1.2Learn MoreLife Sciences CompanyExternal Manufacturing
SOM ESM Take Product SampleB2B Other XML APIEPCIS 1.2Learn MoreLife Sciences CompanyExternal Manufacturing
SOM ESM Country ClearanceB2B Other XML APIEPCIS 1.2Learn MoreLife Sciences CompanyExternal Manufacturing
SOM Country ClearanceB2B Other XML APIEPCIS 1.2Learn MoreLife Sciences CompanyExternal Manufacturing
SOM ESM AggregationB2B Other XML APIEPCIS 1.2Learn MoreLife Sciences CompanyExternal Manufacturing
SOM ESM DisaggregationB2B Other XML APIEPCIS 1.2Learn MoreLife Sciences CompanyExternal Manufacturing
SOM Aggregation UpdateB2B Other XML APIEPCIS 1.2Learn MoreLife Sciences CompanyExternal Manufacturing
SOM ESM Set Recall StatusB2B Other XML APIEPCIS 1.2Learn MoreLife Sciences CompanyExternal Manufacturing
SOM Void ShipmentB2B Other XML APIEPCIS 1.2Learn MoreLife Sciences CompanyExternal Manufacturing
SOM ESM Void ShipmentB2B Other XML APIEPCIS 1.2Learn MoreLife Sciences CompanyExternal Manufacturing
SOM End of BatchB2B Other XML APIEPCIS 1.2Learn MoreLife Sciences CompanyExternal Manufacturing

 

Email

TraceLink supports email-based integration as a lightweight, flexible option for partners who lack the technical infrastructure for direct system-to-system connectivity. This method enables the secure exchange of structured documents—such as XML, CSV, or PDF—through monitored email channels.

Email integration is ideal for small, regional, or low-volume partners, allowing them to participate in digital supply chain workflows without needing an API, ERP connector, or sFTP setup. TraceLink parses incoming documents, validates their contents, and transforms them into network-ready transactions—ensuring full interoperability with your internal systems and other integrated partners.

Key Capabilities
  • Secure, monitored inbound and outbound email channels
  • Support for structured formats: XML, CSV, PDF
  • Automated parsing, validation, and transformation
  • Exception handling and alerting for failed or malformed files
  • Full audit trail and transaction traceability
Benefits
  • Enables universal partner connectivity
  • No technical setup required for small partners
  • Maintains traceability and compliance through the network

Flexible integration for non-integrated or low-tech partners using structured file attachments. Below are common transaction types TraceLink supports via email:

 
TransactionTransaction FormatTransaction Code Business SegmentOrchestration
 B2B Email Learn MoreDirect Material SupplierLogistics

 

sFTP

For partners with batch-based workflows, legacy systems, or limited API capabilities, TraceLink offers sFTP (Secure File Transfer Protocol) as a reliable and secure method for asynchronous data exchange. sFTP enables the scheduled transmission of structured files—such as EPCIS, XML, or CSV—to and from TraceLink’s platform, allowing full participation in digital supply chain processes without requiring real-time connectivity.

This integration method is ideal for high-volume partners, contract manufacturers, or distributors who rely on traditional file-based systems. TraceLink ensures that all incoming and outgoing files are validated, processed, and tracked through its event-driven orchestration engine, providing full visibility and compliance across the network.

Key Capabilities
  • Secure, encrypted file transfer over sFTP protocol
  • Support for structured formats: EPCIS, XML, CSV, PDF
  • File validation, processing, and error reporting
  • Configurable folder structures and naming conventions
  • Full audit trail and transaction traceability
Benefits
  • Compatible with legacy systems and middleware
  • Reliable for high-volume or batch workflows
  • Secure and compliant with full audit trail

Secure, file-based integration for batch workflows and legacy systems. Here are the transaction types supported via sFTP:

 
TransactionTransaction FormatTransaction Code Business SegmentOrchestration
 B2B sFTP Learn MoreDirect Material SupplierLogistics

 

Brazil Pharmaceuticals

How Does TraceLink Support Real-Time Transaction Exchange

Learn how TraceLink MINT enables you and your suppliers to exchange POs, PO acknowledgements, invoices, ASNs, and much more in real time—and see how much it costs!

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Product Information Manager

Reverse Logistics Reconciliation

Automate reverse logistics with serialized EPCIS data and transaction history to reduce compliance risk, manual effort, and rejected returns.

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Why TraceLink for B2B Integration?

Scalable Integration Approach

Event-Driven Architecture

Multi-Modal Flexibility

Rapid Partner Onboarding

Compliance Driven

Supply chain

Scalable Integration Approach

Link once to TraceLink and instantly enable secure, real-time integration with your entire supply chain network. Eliminate the need for custom point-to-point interfaces and scale faster with a unified integration framework.

Expert Strategies

Event-Driven Architecture

Powered by the OPUS platform, TraceLink intelligently orchestrates, validates, and routes transactions in real time—ensuring accurate, timely, and compliant data exchange across all workflows.

Digital Network

Multi-Modal Flexibility

Support for REST APIs, XML payloads, email (SMTP), and sFTP allows you to integrate with partners of any size or technical maturity ensuring universal connectivity across your ecosystem.

integrate

Rapid Partner Onboarding

Onboard new partners in days—not months—with pre-built templates, reusable Link Actions, and configuration accelerators that reduce integration complexity and deployment time.

standardized

Compliance Driven

Natively designed to meet global serialization and traceability regulations, including DSCSA, EU FMD, and Brazil ANVISA helping you stay audit-ready and avoid costly disruptions.

What Our Customers Have to Say

Life sciences leaders are using TraceLink’s B2B APIs to increase agility, automate workflows, and reduce integration overhead. Here's what they’re saying:

raceLink’s APIs helped us reduce order processing time by over 50%. By integrating our ERP with TraceLink’s real-time Order API, we eliminated delays and manual steps—streamlining operations across our global supply chain.

Director of Supply Chain Operations

Global Pharma Company

The real-time data exchange has been a game-changer for our external manufacturing operations. We now have instant visibility into production and shipment status, which helps us manage inventory and timelines with far greater precision.

VP of External Manufacturing

Biotech Company

We integrated with TraceLink’s APIs in weeks—not months—and immediately saw value. The documentation was clear, the support team was responsive, and we were able to go live with multiple partners without building custom middleware.

President

Specialty Pharma Company

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